Есипов Роман Станиславович

Преподаваемая дисциплина:
Создание биотехнологических препаратов

Основные публикации за последние 5 лет:

• Alexeev CS, Drenichev MS, Dorinova EO, Esipov RS, Kulikova IV, Mikhailov SN (2019). Use of nucleoside phosphorylases for the preparation of 5-modified pyrimidine ribonucleosides. BIOCHIM BIOPHYS ACTA 1868 (1), 140292
• Eletskaya BZ, Gruzdev DA, Krasnov VP, Levit GL, Kostromina MA, Paramonov AS, Kayushin AL, Muzyka IS, Muravyova TI, Esipov RS, Andronova VL, Galegov GA, Charushin VN, Miroshnikov AI, Konstantinova ID (2019). Enzymatic Synthesis of Novel Purine Nucleosides Bearing a Chiral Benzoxazine Fragment. Chem Biol Drug Des 93 (4), 605–616
• Zayats EA, Timofeev VI, Kostromina MA, Esipov RS (2018). An explanation for the narrow carbohydrate substrate specificity of adenine phosphoribosyltransferase from Thermus thermophilus from the model of the enzyme, substrate and magnesium cation co-factor complex. J Biomol Struct Dyn 37 (17), 1–5
• Esipov RS, Timofeev VI, Sinitsyna EV, Tuzova ES, Esipova LV, Kostromina MA, Kuranova IP, Miroshnikov AI (2018). Three-Dimensional Structure of Recombinant Adenine Phosphoribosyltransferase from Thermophilic Bacterial Strain Thermus thermophilus HB27. J. Bioorganic Chem. 44 (5), 504–510
• Sinitsyna EV, Timofeev VI, Zhukhlistova NE, Muravieva TI, Kostromina MA, Esipov RS, Kuranova IP (2018). Crystallization and Preliminary X-ray Diffraction Study of Purine Nucleoside Phosphorylase from the Thermophilic Bacterium Thermus thermophilus Strain HB27. CRYSTALLOGR REP+ 63 (5), 761–764
• Timofeev VI, Zhukhlistova NE, Abramchik YA, Muravieva TI, Esipov RS, Kuranova IP (2018). Crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with acyclovir. Acta Crystallogr F Struct Biol Commun 74 (7), 402–409
• Timofeev VI, Zhukhlistova NE, Abramchik YA, Fateev II, Kostromina MA, Muravieva TI, Esipov RS, Kuranova IP (2018). Crystal structure of Escherichia coli purine nucleoside phosphorylase in complex with 7-deazahypoxanthine. Acta Crystallogr F Struct Biol Commun 74 (Pt 6), 355–362
• Esipov RS, Makarov DA, Stepanenko VN, Kostromina MA, Muravyova TI, Andreev YA, Dyachenko IA, Kozlov SA, Grishin EV (2018). Pilot production of the recombinant peptide toxin of Heteractis crispa as a potential analgesic by intein-mediated technology. Protein Expr Purif 145, 71–76
• Esipov RS, Stepanenko VN, Zvereva IO, Makarov DA, Kostromina MA, Kostromina TI, Muravyova TI, Miroshnikov AI, Grishin EV (2018). Biotechnological Method for Production of Recombinant Peptide Analgesic (Purotoxin-1) from Geolycosa sp. Spider Poison. J. Bioorganic Chem. 44 (1), 32–40
• Simonova MA, Pivovarov VD, Ryazantsev DY, Kostromina MA, Muravieva TI, Mokronosova MA, Khlgatian SV, Esipov RS, Zavriev SK (2018). Determination of Specific Class E Immunoglobulins to Bet v 1 Birch Allergen by the Immuno-PCR Method. J. Bioorganic Chem. 44 (2), 217–224
• СимоноваМА, Пивоваров ВД, Рязанцев ДЮ, Костромина МА, Муравьева ТИ, Мокроносова МА, Хлгатьян СВ, Есипов РС, Завриев СК (2018). Определение специфических иммуноглобулинов класса Е к аллергену березы Bet v 1 методом иммуно-ПЦР. 44, 203–211
• Denisova AO, Tokunova YA, Fateev IV, Breslav AA, Leonov VN, Dorofeeva EV, Lutonina OI, Muzyka IS, Esipov RS, Kayushin AL, Konstantinova ID, Miroshnikov AI, Stepchenko VA, Mikhailopulo IA (2017). The Chemoenzymatic Synthesis of 2-Chloro- and 2-Fluorocordycepins. Synthesis (Stuttg) 49 (21), 4853–4860
• Sinitsyna EV, Timofeev VI, Tuzova ES, Kostromina MA, Muraveva TI, Esipov RS, Kuranova IP (2017). Crystallization and preliminary X-ray diffraction study of recombinant adenine phosphoribosyltransferase from the thermophilic bacterium Thermus thermophilus strain HB27. CRYSTALLOGR REP+ 62 (4), 580–583
• Timofeev VI, Sinitsyna EV, Kostromina MA, Muravieva TI, Makarov DA, Mikheeva OO, Kuranova IP, Esipov RS (2017). Crystal structure of recombinant phosphoribosylpyrophosphate synthetase 2 from Thermus thermophilus HB27 complexed with ADP and sulfate ions. Acta Crystallogr F Struct Biol Commun 73 (6), 369–375
• Abramchik YA, Timofeev VI, Muravieva TI, Sinitsyna EV, Esipov RS, Kuranova IP (2017). Crystallization and preliminary X-ray diffraction analysis of recombinant phosphoribosylpyrophosphate synthetase from the Thermophilic thermus thermophilus strain HB27. CRYSTALLOGR REP+ 62 (1), 78–81
• Abramchik YA, Timofeev VI, Muravieva TI, Esipov RS, Kuranova IP (2016). Crystallization and preliminary X-ray diffraction study of recombinant ribokinase from Thermus Species 2.9. CRYSTALLOGR REP+ 61 (6), 974–978
• Esipov RS, Abramchik YA, Fateev IV, Muravyova TI, Artemova KG, Konstantinova ID, Kuranova IP, Miroshnikov AI (2016). Recombinant phosphoribosyl pyrophosphate synthetases from Thermus thermophilus HB27: Isolation and properties. J. Bioorganic Chem. 42 (5), 512–521
• Esipov RS, Makarov DA, Stepanenko VN, Miroshnikov AI (2016). Development of the intein-mediated method for production of recombinant thymosin β4 from the acetylated in vivo fusion protein. J Biotechnol 228, 73–81
• Esipov RS, Abramchik YA, Fateev IV, Konstantinova ID, Kostromina MA, Muravyova TI, Artemova KG, Miroshnikov AI (2016). A Cascade of Thermophilic Enzymes As an Approach to the Synthesis of Modified Nucleotides. Acta Naturae 8 (4), 82–90
• Eletskaya BZ, Konstantinova ID, Paramonov AS, Esipov RS, Gruzdev DA, Vigorov AY, Levit GL, Miroshnikov AI, Krasnov VP, Charushin VN (2016). Chemoenzymatic arabinosylation of 2-aminopurines bearing the chiral fragment of 7,8-difluoro-3-methyl-3,4-dihydro-2H-[1,4]benzoxazines. MENDELEEV COMMUN 26 (1), 6–8
• Макаров ДА, Есипов РС (2016). Разработка способов получения аналогов тимозин-бета 4 в виде коньюгатов, устойчивых к деградации в токе крови. Biotekhnologiya 32 (2), 57–71
• Timofeev VI, Chupova LA, Esipov RS, Kuranova IP (2015). Crystallization and preliminary X-ray diffraction study of phosphopantetheine adenylyltransferase from M. tuberculosis crystallizing in space group P32. CRYSTALLOGR REP+ 60 (5), 682–684
• Fateev IV, Kharitonova MI, Antonov KV, Konstantinova ID, Stepanenko VN, Esipov RS, Seela F, Temburnikar KW, Seley-Radtke KL, Stepchenko VA, Sokolov YA, Miroshnikov AI, Mikhailopulo IA (2015). Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides. Chemistry 21 (38), 13401–13419
• Esipov RS, Kostromina MA (2015). Comparative Analysis of the Effectiveness of C-terminal Cleavage Intein-Based Constructs in Producing a Recombinant Analog of Anophelin, an Anticoagulant from Anopheles albimanus. Appl Biochem Biotechnol 175 (5), 2468–2488